Structure of PDB 1i4f Chain A Binding Site BS01
Receptor Information
>1i4f Chain A (length=275) Species:
9606
(Homo sapiens) [
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GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
Ligand information
>1i4f Chain C (length=10) Species:
9606
(Homo sapiens) [
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GVYDGREHTV
Receptor-Ligand Complex Structure
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PDB
1i4f
High-resolution structure of HLA-A*0201 in complex with a tumour-specific antigenic peptide encoded by the MAGE-A4 gene.
Resolution
1.4 Å
Binding residue
(original residue number in PDB)
Y7 E63 K66 H70 T73 V76 D77 Y84 Y99 T143 K146 W147 V152 Q155 Y159 T163 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 E63 K66 H70 T73 V76 D77 Y84 Y99 T143 K146 W147 V152 Q155 Y159 T163 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:1i4f
,
PDBe:1i4f
,
PDBj:1i4f
PDBsum
1i4f
PubMed
11502003
UniProt
P04439
|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)
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