Structure of PDB 1hsa Chain A Binding Site BS01
Receptor Information
>1hsa Chain A (length=276) Species:
9606
(Homo sapiens) [
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GSHSMRYFHTSVSRPGRGEPRFITVGYVDDTLFVRFDSDAASPREEPRAP
WIEQEGPEYWDRETQICKAKAQTDREDLRTLLRYYNQSEAGSHTLQNMYG
CDVGPDGRLLRGYHQDAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
RVAEQLRAYLEGECVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
>1hsa Chain C (length=9) [
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ARAAAAAAA
Receptor-Ligand Complex Structure
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PDB
1hsa
The three-dimensional structure of HLA-B27 at 2.1 A resolution suggests a general mechanism for tight peptide binding to MHC.
Resolution
2.1 Å
Binding residue
(original residue number in PDB)
Y7 H9 T24 E45 R62 E63 I66 C67 D77 Y84 Y99 T143 W147 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 H9 T24 E45 R62 E63 I66 C67 D77 Y84 Y99 T143 W147 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:1hsa
,
PDBe:1hsa
,
PDBj:1hsa
PDBsum
1hsa
PubMed
1525820
UniProt
P01889
|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)
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