Structure of PDB 1hlz Chain A Binding Site BS01

Receptor Information
>1hlz Chain A (length=81) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VLLCKVCGDVASGFHYGVLACEGCKGFFRRSIQQNIQYKRCLKNENCSIV
RINRNRCQQCRFKKCLSVGMSRDAVRFGRIP
Ligand information
Receptor-Ligand Complex Structure
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PDB1hlz DNA Deformability as a Recognition Feature in the RevErb Response Element
Resolution2.8 Å
Binding residue
(original residue number in PDB)
G10 F11 H12 K22 R26 R68 V71 F73 G74 I76
Binding residue
(residue number reindexed from 1)
G13 F14 H15 K25 R29 R72 V75 F77 G78 I80
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:1hlz, PDBe:1hlz, PDBj:1hlz
PDBsum1hlz
PubMed11669620
UniProtP20393|NR1D1_HUMAN Nuclear receptor subfamily 1 group D member 1 (Gene Name=NR1D1)

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