Structure of PDB 1hes Chain A Binding Site BS01

Receptor Information
>1hes Chain A (length=256) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSG
MPECKFGMNDKIKQSIAIDDCTFHQCVRLSERSISFIPPDGEFELMRYRT
TKDIILPFRVIPLVREVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPTPLN
TSGVQVICMKGKAKYKASENAIVWKIKRMAGMKESQISAEIELLPTNDKK
KWARPPISMNFEVPFAPSGLKVRYLKVFEPKLNYSDHDVIKWVRYIGRSG
IYETRC
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1hes A Third Specificity-Determining Site in Mu 2 Adaptin for Sequences Upstream of Yxx Phi Sorting Motifs
Resolution3.0 Å
Binding residue
(original residue number in PDB)		D176 Q318 E391 V392 P393 K420 W421 V422 R423
Binding residue
(residue number reindexed from 1)		D18 Q139 E212 V213 P214 K241 W242 V243 R244
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0030131 clathrin adaptor complex

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Biological Process
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Cellular Component
External links
PDB RCSB:1hes, PDBe:1hes, PDBj:1hes
PDBsum1hes
PubMed11247301
UniProtP84092|AP2M1_RAT AP-2 complex subunit mu (Gene Name=Ap2m1)

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