Structure of PDB 1h8t Chain A Binding Site BS01

Receptor Information
>1h8t Chain A (length=289) Species: 12078 (Echovirus E11) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GDVVEAVENAVARVADTIGSGPSNSQAVPALTAVETGHTSQVTPSDTVQT
RHVKNYHSRSESSIENFLSRSACVYMGEYHTTNSDQTKLFASWTISARRM
VQMRRKLEIFTYVRFDVEVTFVITSKQDQGTQLGQDMPPLTHQIMYIPPG
GPIPKSVTDYTWQTSTNPSIFWTEGNAPPRMSIPFISIGNAYSNFYDGWS
HFSQNGVYGYNTLNHMGQIYVRHVNGSSPLPMTSTVRMYFKPKHVKAWVP
RPPRLCQYKNASTVNFSPTDITDKRNSITYIPDTVKPDV
Ligand information
Ligand IDDOA
InChIInChI=1S/C12H25NO2/c13-11-9-7-5-3-1-2-4-6-8-10-12(14)15/h1-11,13H2,(H,14,15)
InChIKeyPBLZLIFKVPJDCO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04O=C(O)CCCCCCCCCCCN
OpenEye OEToolkits 1.5.0C(CCCCCC(=O)O)CCCCCN
CACTVS 3.341NCCCCCCCCCCCC(O)=O
FormulaC12 H25 N O2
Name12-AMINO-DODECANOIC ACID
ChEMBLCHEMBL371701
DrugBank
ZINCZINC000001845814
PDB chain1h8t Chain A Residue 1000 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1h8t Determination of the Structure of a Decay Accelerating Factor-Binding Clinical Isolate of Echovirus 11 Allows Mapping of Mutants with Altered Receptor Requirements for Infection
Resolution2.9 Å
Binding residue
(original residue number in PDB)		I95 Y192 M216
Binding residue
(residue number reindexed from 1)		I95 Y192 M216
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:1h8t, PDBe:1h8t, PDBj:1h8t
PDBsum1h8t
PubMed12097583
UniProtQ8JKE8

[Back to BioLiP]