Structure of PDB 1h56 Chain A Binding Site BS01

Receptor Information

>1h56 Chain A (length=156) Species: 585 (Proteus vulgaris) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SHPDLNKLLELWPHIQEYQDLALKHGINDIFQDNGGKLLQVLLITGLTVL
PGREGNDAVDNAGQEYELKSINIDLTKGFSTHHHMNPVIIAKYRQVPWIF
AIYRGIAIEAIYRLEPKDLEFYYDKWERKWYSDGHKDINNPKIPVKYVME
HGTKIY

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

1h56 Chain A Residue 1 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	1h56 Structural and Biochemical Characterization of a New Mg(2+) Binding Site Near Tyr94 in the Restriction Endonuclease PvuII.
Resolution	3.0 Å
Binding residue (original residue number in PDB)	D58 E68
Binding residue (residue number reindexed from 1)	D57 E67
Annotation score	4

Enzymatic activity

Catalytic site (original residue number in PDB)	D58 E68 K70
Catalytic site (residue number reindexed from 1)	D57 E67 K69
Enzyme Commision number	3.1.21.4: type II site-specific deoxyribonuclease.

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0004519	endonuclease activity
GO:0009036	type II site-specific deoxyribonuclease activity
GO:0046872	metal ion binding

	Biological Process
GO:0009307	DNA restriction-modification system

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Molecular Function

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External links

PDB	RCSB:1h56, PDBe:1h56, PDBj:1h56
PDBsum	1h56
PubMed	12888347
UniProt	P23657\|T2P2_PROHU Type II restriction enzyme PvuII (Gene Name=pvuIIR)

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