Structure of PDB 1h30 Chain A Binding Site BS01

Receptor Information

>1h30 Chain A (length=391) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

HCDGRGGLKLSQDMDTCEDILPCVPFSVAKSVKSLYLGRPVIRLRFKRLQ
PTRLVAEFDFRTFDPEGILLFAGGHQDSTWIVLALRAGRLELQLRYNGVG
RVTSSGPVINHGMWQTISVEELARNLVIKVNRDAVMKIAVAGDLFQPERG
LYHLNLTVGGIPFHEKDLVQPINPRLDGCMRSWNWLTVKVNTRMQCFSVT
ERGSFYPGSGFAFYSLDYMRSTWEVEVVAHIRPAADTGVLFALWAPDLRA
VPLSVALVDYHKKQLVVLAVEHTALALMEIKVCDGQEHVVTVSLRDGEAT
LEVDGTRGQSEVSAAQLQERLAVLERHLRSPVLTFAGGLPDVPVTSAPVT
AFYRGCMTLEVNRRLLDLDEAAYKHSDITAHSCPPVEPAAA

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

1h30 Chain A Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	1h30 Crystal Structure of a Carboxy-Terminal Fragment of Growth-Arrest-Specific Protein Gas6: Receptor Tyrosine Kinase Activation by Laminin G-Like Domains
Resolution	2.2 Å
Binding residue (original residue number in PDB)	D329 E331 R440 D656 H668
Binding residue (residue number reindexed from 1)	D64 E66 R175 D369 H381
Annotation score	4

Enzymatic activity

Enzyme Commision number

External links

PDB	RCSB:1h30, PDBe:1h30, PDBj:1h30
PDBsum	1h30
PubMed	12218057
UniProt	Q14393\|GAS6_HUMAN Growth arrest-specific protein 6 (Gene Name=GAS6)

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