Structure of PDB 1gxc Chain A Binding Site BS01

Receptor Information
>1gxc Chain A (length=116) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PWARLWALQDGFANLECVNDNYWFGRDKSCEYCFDEPLLKRTDKYRTYSK
KHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNSEIAL
SLSRNKVFVFFDLTVD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1gxc Structural and Functional Versatility of the Fha Domain in DNA-Damage Signaling by the Tumor Suppressor Kinase Chk2
Resolution2.7 Å
Binding residue
(original residue number in PDB)
R117 D118 Y136 R137 T138 S140 K141 N166 S192
Binding residue
(residue number reindexed from 1)
R26 D27 Y45 R46 T47 S49 K50 N75 S101
Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
External links
PDB RCSB:1gxc, PDBe:1gxc, PDBj:1gxc
PDBsum1gxc
PubMed12049740
UniProtO96017|CHK2_HUMAN Serine/threonine-protein kinase Chk2 (Gene Name=CHEK2)

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