Structure of PDB 1gwr Chain A Binding Site BS01

Receptor Information
>1gwr Chain A (length=238) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LALSLTADQMVSALLDAEPPILYSEYRPFSEASMMGLLTNLADRELVHMI
NWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNL
LLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGV
YTFTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLIL
SHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1gwr Interaction of Transcriptional Intermediary Factor 2 Nuclear Receptor Box Peptides with the Coactivator Binding Site of Estrogen Receptor Alpha.
Resolution2.4 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 E542
Binding residue
(residue number reindexed from 1)
I50 K54 L64 V68 E231
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:1gwr, PDBe:1gwr, PDBj:1gwr
PDBsum1gwr
PubMed11937504
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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