Structure of PDB 1gwq Chain A Binding Site BS01

Receptor Information
>1gwq Chain A (length=243) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SKKNSLALSLTADQMVSALLDAEPPILYSEPFSEASMMGLLTNLADRELV
HMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFA
PNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLN
SGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLA
QLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1gwq Interaction of Transcriptional Intermediary Factor 2 Nuclear Receptor Box Peptides with the Coactivator Binding Site of Estrogen Receptor Alpha.
Resolution2.45 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 D538 L539 E542 M543
Binding residue
(residue number reindexed from 1)
I53 K57 L67 D233 L234 E237 M238
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:1gwq, PDBe:1gwq, PDBj:1gwq
PDBsum1gwq
PubMed11937504
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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