Structure of PDB 1gts Chain A Binding Site BS01

Receptor Information
>1gts Chain A (length=529) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TNFIRQIIDEDLASGKHTTVHTRFPPEPNGYLHIGHAKSICLNFGIAQDY
KGQCNLRFDDTNPVKEDIEYVESIKNDVEWLGFHWSGNVRYSSDYFDQLH
AYAIELINKGLAYVDELTPEQIREYRGTLTQPGKNSPYRDRSVEENLALF
EKMRAGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQTGNKWCI
YPMYDFTHCISDALEGITHSLCTLEFQDNRRLYDWVLDNITIPVHPRQYE
FSRLNLEYTVMSKRKLNLLVTDKHVEGWDDPRMPTISGLRRRGYTAASIR
EFCKRIGVTKQDNTIEMASLESCIREDLNENAPRAMAVIDPVKLVIENYQ
GEGEMVTMPNHPNKPEMGSRQVPFSGEIWIDRADFREEANKQYKRLVLGK
EVRLRNAYVIKAERVEKDAEGNITTIFCTYDADTLGVIHWVSAAHALPVE
IRLYDRLFSVPNPGAADDFLSVINPESLVIKQGFAEPSLKDAVAGKAFQF
EREGYFCLDSRHSTAEKPVFNRTVGLRDT
Ligand information
>1gts Chain B (length=74) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gggguaucgccaagcgguaaggcaccggauucugauuccggcauuccgag
guucgaauccucguaccccagcca
<<<<<<..<<<.........>>>.<<<<<.......>>>>>.....<<<<
<.......>>>>>>>>>>>.....
Receptor-Ligand Complex Structure
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PDB1gts Structural basis for transfer RNA aminoacylation by Escherichia coli glutaminyl-tRNA synthetase.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		Q13 E34 D66 T68 N69 P126 R133 L136 G168 P181 F182 I183 V189 R192 K194 M210 Y211 F233 Q234 D235 I313 T316 K317 Q318 N320 T321 E323 A325 S329 N336 R341 Q399 Y400 K401 R402 R410 R412 N413 V455 E519 R520 R545 T547
Binding residue
(residue number reindexed from 1)		Q6 E27 D59 T61 N62 P119 R126 L129 G161 P174 F175 I176 V182 R185 K187 M203 Y204 F226 Q227 D228 I306 T309 K310 Q311 N313 T314 E316 A318 S322 N329 R334 Q392 Y393 K394 R395 R403 R405 N406 V437 E501 R502 R527 T529
Enzymatic activity
Enzyme Commision number 6.1.1.18: glutamine--tRNA ligase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004819 glutamine-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0006412 translation
GO:0006418 tRNA aminoacylation for protein translation
GO:0006424 glutamyl-tRNA aminoacylation
GO:0006425 glutaminyl-tRNA aminoacylation
GO:0043039 tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1gts, PDBe:1gts, PDBj:1gts
PDBsum1gts
PubMed8364025
UniProtP00962|SYQ_ECOLI Glutamine--tRNA ligase (Gene Name=glnS)

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