Structure of PDB 1gnf Chain A Binding Site BS01

Receptor Information
>1gnf Chain A (length=46) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSEARECVNCGATATPLWRRDRTGHYLCNACGLYHKMNGQNRPLIR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1gnf Chain A Residue 244 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1gnf The solution structure of the N-terminal zinc finger of GATA-1 reveals a specific binding face for the transcriptional co-factor FOG.
ResolutionN/A
Binding residue
(original residue number in PDB)		C204 C207 C225 C228
Binding residue
(residue number reindexed from 1)		C7 C10 C28 C31
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:1gnf, PDBe:1gnf, PDBj:1gnf
PDBsum1gnf
PubMed10212985
UniProtP17679|GATA1_MOUSE Erythroid transcription factor (Gene Name=Gata1)

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