Structure of PDB 1gkp Chain A Binding Site BS01

Receptor Information

>1gkp Chain A (length=458) Species: 275 (Thermus sp.) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

PLLIKNGEIITADSRYKADIYAEGETITRIGQNLEAPPGTEVIDATGKYV
FPGFIDPHVHIYLPFMATFAKDTHETGSKAALMGGTTTYIEMCCPSRNDD
ALEGYQLWKSKAEGNSYCDYTFHMAVSKFDEKTEGQLREIVADGISSFKI
FLSYKNFFGVDDGEMYQTLRLAKELGVIVTAHCENAELVGRLQQKLLSEG
KTGPEWHEPSRPEAVEAEGTARFATFLETTGATGYVVHLSCKPALDAAMA
AKARGVPIYIESVIPHFLLDKTYAERGGVEAMKYIMSPPLRDKRNQKVLW
DALAQGFIDTVGTDHCPFDTEQKLLGKEAFTAIPNGIPAIEDRVNLLYTY
GVSRGRLDIHRFVDAASTKAAKLFGLFPRKGTIAVGSDADLVVYDPQYRG
TISVKTQHVNNDYNGFEGFEIDGRPSVVTVRGKVAVRDGQFVGEKGWGKL
LRREPMYF

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

1gkp Chain A Residue 1460 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	1gkp X-Ray Structure of a Dihydropyrimidinase from Thermus Sp. At 1.3 A Resolution
Resolution	1.295 Å
Binding residue (original residue number in PDB)	K150 H183 H239
Binding residue (residue number reindexed from 1)	K149 H182 H238
Annotation score	1

Enzymatic activity

Enzyme Commision number

3.5.2.2: dihydropyrimidinase.

Gene Ontology

	Molecular Function
GO:0016787	hydrolase activity
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0046872	metal ion binding

	Cellular Component
GO:0005737	cytoplasm

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Molecular Function

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Cellular Component

External links

PDB	RCSB:1gkp, PDBe:1gkp, PDBj:1gkp
PDBsum	1gkp
PubMed	12079340
UniProt	Q7SIE9

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