Structure of PDB 1g38 Chain A Binding Site BS01

Receptor Information
>1g38 Chain A (length=393) Species: 271 (Thermus aquaticus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VETPPEVVDFMVSLAEAPRGGRVLEPACAHGPFLRAFREAHGTGYRFVGV
EIDPKALDLPPWAEGILADFLLWEPGEAFDLILGNPPYGIVGEASKYPIH
VFKAVKDLYKKAFSTWKGKYNLYGAFLEKAVRLLKPGGVLVFVVPATWLV
LEDFALLREFLAREGKTSVYYLGEVFPQKKVSAVVIRFQKSGKGLSLWDT
QESESGFTPILWAEYPHWEGEIIRFETEETRKLEISGMPLGDLFHIRFAA
RSPEFKKHPAVRKEPGPGLVPVLTGRNLKPGWVDYEKNHSGLWMPKERAK
ELRDFYATPHLVVAHTKGTRVVAAWDERAYPWREEFHLLPKEGVRLDPSS
LVQWLNSEAMQKHVRTLYRDFVPHLTLRMLERLPVRREYGFHT
Ligand information
Receptor-Ligand Complex Structure
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PDB1g38 Structure of the N6-adenine DNA methyltransferase M.TaqI in complex with DNA and a cofactor analog.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		V21 N105 P106 Y108 K139 T167 L171 D173 F196 K199 K200 F268 R271 R323 P393 H394
Binding residue
(residue number reindexed from 1)		V1 N85 P86 Y88 K119 T147 L151 D153 F176 K179 K180 F248 R251 R303 P373 H374
Enzymatic activity
Enzyme Commision number 2.1.1.72: site-specific DNA-methyltransferase (adenine-specific).
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0008168 methyltransferase activity
GO:0009007 site-specific DNA-methyltransferase (adenine-specific) activity
Biological Process
GO:0006304 DNA modification
GO:0009307 DNA restriction-modification system
GO:0032259 methylation

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Molecular Function
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Biological Process
External links
PDB RCSB:1g38, PDBe:1g38, PDBj:1g38
PDBsum1g38
PubMed11175899
UniProtP14385|MTTA_THEAQ Type II methyltransferase M.TaqI (Gene Name=taqIM)

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