Structure of PDB 1fyr Chain A Binding Site BS01
Receptor Information
>1fyr Chain A (length=95) Species:
9606
(Homo sapiens) [
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HPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQH
FKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIE
Ligand information
>1fyr Chain I (length=4) Species:
9606
(Homo sapiens) [
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YVNV
Receptor-Ligand Complex Structure
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PDB
1fyr
Dimer formation through domain swapping in the crystal structure of the Grb2-SH2-Ac-pYVNV complex.
Resolution
2.4 Å
Binding residue
(original residue number in PDB)
R67 R86 S88 E89 S90 S96 H107 F108 K109 W121
Binding residue
(residue number reindexed from 1)
R10 R29 S31 E32 S33 S39 H50 F51 K52 W64
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:1fyr
,
PDBe:1fyr
,
PDBj:1fyr
PDBsum
1fyr
PubMed
11063574
UniProt
P62993
|GRB2_HUMAN Growth factor receptor-bound protein 2 (Gene Name=GRB2)
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