Structure of PDB 1fyn Chain A Binding Site BS01

Receptor Information

>1fyn Chain A (length=62) Species: 9606 (Homo sapiens)

GTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGET
GYIPSNYVAPVD

Ligand information

>1fyn Chain B (length=10)

PPAYPPPPVP

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1fyn High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides.
• Resolution: 2.3 Å
• Binding residue (original residue number in PDB): Y91 R96 E116 W119 Y132 N136 Y137
• Binding residue (residue number reindexed from 1): Y11 R16 E36 W39 Y52 N56 Y57

Enzymatic activity

• Enzyme Commision number: 2.7.10.2: non-specific protein-tyrosine kinase.

External links

• PDB: RCSB:1fyn, PDBe:1fyn, PDBj:1fyn
• PDBsum: 1fyn
• PubMed: 7664083
• UniProt: P06241|FYN_HUMAN Tyrosine-protein kinase Fyn (Gene Name=FYN)