Structure of PDB 1fua Chain A Binding Site BS01

Receptor Information
>1fua Chain A (length=206) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MERNKLARQIIDTCLEMTRLGLNQGTAGNVSVRYQDGMLITPTGIPYEKL
TESHIVFIDGNGKHEEGKLPSSEWRFHMAAYQSRPDANAVVHNHAVHCTA
VSILNRSIPAIHYMIAAAGGNSIPCAPYATFGTRELSEHVALALKNRKAT
LLQHHGLIACEVNLEKALWLAHEVEVLAQLYLTTLAITDPVPVLSDEEIA
VVLEKF
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1fua Chain A Residue 216 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1fua Refined high-resolution structure of the metal-ion dependent L-fuculose-1-phosphate aldolase (class II) from Escherichia coli.
Resolution1.92 Å
Binding residue
(original residue number in PDB)		E73 H92 H94 H155
Binding residue
(residue number reindexed from 1)		E73 H92 H94 H155
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) E73 H92 H94 Y113 A117 H155
Catalytic site (residue number reindexed from 1) E73 H92 H94 Y113 A117 H155
Enzyme Commision number 4.1.2.17: L-fuculose-phosphate aldolase.
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0008738 L-fuculose-phosphate aldolase activity
GO:0016829 lyase activity
GO:0016830 carbon-carbon lyase activity
GO:0016832 aldehyde-lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0005996 monosaccharide metabolic process
GO:0006004 fucose metabolic process
GO:0019317 fucose catabolic process
GO:0019323 pentose catabolic process
GO:0019568 arabinose catabolic process
GO:0019571 D-arabinose catabolic process
GO:0042355 L-fucose catabolic process
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:1fua, PDBe:1fua, PDBj:1fua
PDBsum1fua
PubMed15299567
UniProtP0AB87|FUCA_ECOLI L-fuculose phosphate aldolase (Gene Name=fucA)

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