Structure of PDB 1fok Chain A Binding Site BS01

Receptor Information
>1fok Chain A (length=568) Species: 244 (Planomicrobium okeanokoites) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KIRTFGWVQNPGKFENLKRVVQVFDRNSKVHNEVKNIKIPTLVKESKIQK
ELVAIMNQHDLIYTYKELVGTGTSIRSEAPCDAIIQATIADQGNKKGYID
NWSSDGFLRWAHALGFIEYINKSDSFVITDVGLAYSKSADGSAIEKEILI
EAISSYPPAIRILTLLEDGQHLTKFDLGKNLGFSGESGFTSLPEGILLDT
LANAMPKDKGEIRNNWEGSSDKYARMIGGWLDKLGLVKQGKKEFIIPTPD
NKEFISHAFKITGEGLKVLRRAKGSVPKRVYWEMLATNLTDKEYVRTRRA
LILEILIKAGSLKIEQIQDNLKKLGFDEVIETIENDIKGLINTGIFIEIK
GRFYQLKDHILQFVIPNRGVTKQLVKSELEEKKSELRHKLKYVPHEYIEL
IEIARNSTQDRILEMKVMEFFMKVYGYRGKHLGGSRKPDGAIYTVGSPID
YGVIVDTKAYSGGYNLPIGQADEMQRYVEENQTRNKHINPNEWWKVYPSS
VTEFKFLFVSGHFKGNYKAQLTRLNHITNCNGAVLSVEELLIGGEMIKAG
TLTLEEVRRKFNNGEINF
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1fok Structure of the multimodular endonuclease FokI bound to DNA.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		N13 G15 K16 S77 I78 R79 Q95 I102 S106 F110 N217 K225 R228 H263
Binding residue
(residue number reindexed from 1)		N10 G12 K13 S74 I75 R76 Q92 I99 S103 F107 N214 K222 R225 H257
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:1fok, PDBe:1fok, PDBj:1fok
PDBsum1fok
PubMed9214510
UniProtP14870|T2F1_PLAOK Type II restriction enzyme FokI (Gene Name=fokIR)

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