Structure of PDB 1fiv Chain A Binding Site BS01

Receptor Information
>1fiv Chain A (length=113) Species: 11673 (Feline immunodeficiency virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VGTTTTLEKRPEILIFVNGYPIKFLLDTGADITILNRRDFQVKNSIENGR
QNMIGVGGGKRGTNYINVHLEIRDENYKTQCIFGNVCVLEDNSLIQPLLG
RDNMIKFNIRLVM
Ligand information
Receptor-Ligand Complex Structure
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PDB1fiv Structure of an inhibitor complex of the proteinase from feline immunodeficiency virus.
Resolution2.0 Å
Binding residue
(original residue number in PDB)
L28 D30 G32 A33 D34 M56 I57 G58 Q99
Binding residue
(residue number reindexed from 1)
L25 D27 G29 A30 D31 M53 I54 G55 Q96
Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
3.4.23.-
3.6.1.23: dUTP diphosphatase.
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function

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Biological Process
External links
PDB RCSB:1fiv, PDBe:1fiv, PDBj:1fiv
PDBsum1fiv
PubMed7664111
UniProtP16088|POL_FIVPE Pol polyprotein (Gene Name=pol)

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