Structure of PDB 1fic Chain A Binding Site BS01

Receptor Information
>1fic Chain A (length=260) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTV
FQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIP
YALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGF
DFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGH
LNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLT
IGEGQQHHLG
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1fic Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1fic Crystal structure of a 30 kDa C-terminal fragment from the gamma chain of human fibrinogen.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		D318 D320 F322 E323 G324
Binding residue
(residue number reindexed from 1)		D175 D177 F179 E180 G181
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0007596 blood coagulation

View graph for
Biological Process
External links
PDB RCSB:1fic, PDBe:1fic, PDBj:1fic
PDBsum1fic
PubMed9016719
UniProtP02679|FIBG_HUMAN Fibrinogen gamma chain (Gene Name=FGG)

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