Structure of PDB 1fib Chain A Binding Site BS01

Receptor Information
>1fib Chain A (length=249) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTV
FQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIP
YALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGF
DFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGH
LNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRL
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1fib Chain A Residue 500 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1fib Crystal structure of a 30 kDa C-terminal fragment from the gamma chain of human fibrinogen.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		D318 D320 F322 G324
Binding residue
(residue number reindexed from 1)		D175 D177 F179 G181
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0007596 blood coagulation

View graph for
Biological Process
External links
PDB RCSB:1fib, PDBe:1fib, PDBj:1fib
PDBsum1fib
PubMed9016719
UniProtP02679|FIBG_HUMAN Fibrinogen gamma chain (Gene Name=FGG)

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