Structure of PDB 1fhb Chain A Binding Site BS01

Receptor Information

>1fhb Chain A (length=108) Species: 4932 (Saccharomyces cerevisiae)

TEFKAGSAKKGATLFKTRCLQCHTVEKGGPHKVGPNLHGIFGRQSGQAEG
YSYTDANIKKNVLWDENNMSEYLTNPKKYIPGTKAAFGGLKKEKDRNDLI
TYLKKASE

Ligand information

• Ligand ID: CYN
• InChI: InChI=1S/CN/c1-2/q-1
• InChIKey: XFXPMWWXUTWYJX-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  CACTVS 3.341
  OpenEye OEToolkits 1.5.0: [C-]#N
• Formula: C N
• Name: CYANIDE ION
• PDB chain: 1fhb Chain A Residue 105

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1fhb Three-Dimensional Solution Structure of the Cyanide Adduct of a met80Ala Variant of Saccharomyces Cerevisiae Iso-1-Cytochrome C. Identification of Ligand-Residue Interactions in the Distal Heme Cavity
• Resolution: N/A
• Binding residue (original residue number in PDB): Y67 P71 A80
• Binding residue (residue number reindexed from 1): Y72 P76 A85
• Annotation score: 3

Gene Ontology

Molecular Function

• GO:0005515 protein binding
• GO:0009055 electron transfer activity
• GO:0020037 heme binding
• GO:0046872 metal ion binding
• GO:1901612 cardiolipin binding

Biological Process

• GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c
• GO:0006123 mitochondrial electron transport, cytochrome c to oxygen

Cellular Component

• GO:0005739 mitochondrion
• GO:0005758 mitochondrial intermembrane space

External links

• PDB: RCSB:1fhb, PDBe:1fhb, PDBj:1fhb
• PDBsum: 1fhb
• PubMed: 7547866
• UniProt: P00044|CYC1_YEAST Cytochrome c isoform 1 (Gene Name=CYC1)