Structure of PDB 1fga Chain A Binding Site BS01

Receptor Information
>1fga Chain A (length=124) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PKRLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVC
ANRYLAMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKYTSWYVALK
RTGQYKLGSKTGPGQKAILFLPMS
Ligand information
Ligand IDSE4
InChIInChI=1S/H2O4Se/c1-5(2,3)4/h(H2,1,2,3,4)/p-2
InChIKeyQYHFIVBSNOWOCQ-UHFFFAOYSA-L
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341		[O-][Se]([O-])(=O)=O
OpenEye OEToolkits 1.5.0[O-][Se](=O)(=O)[O-]
FormulaO4 Se
NameSELENATE ION
ChEMBL
DrugBank
ZINC
PDB chain1fga Chain A Residue 147 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1fga Refinement of the structure of human basic fibroblast growth factor at 1.6 A resolution and analysis of presumed heparin binding sites by selenate substitution.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		N27 K119 R120 K125
Binding residue
(residue number reindexed from 1)		N8 K100 R101 K106
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008083 growth factor activity

View graph for
Molecular Function
External links
PDB RCSB:1fga, PDBe:1fga, PDBj:1fga
PDBsum1fga
PubMed7691311
UniProtP09038|FGF2_HUMAN Fibroblast growth factor 2 (Gene Name=FGF2)

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