Structure of PDB 1f1w Chain A Binding Site BS01

Receptor Information
>1f1w Chain A (length=104) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MAEEWYFGKITRRESERLLLNPENPRGTFLVRESETTKGAYCLSVSDFDN
AKGLNVKHYKIRKLDSGGFYIWSRTQFSSLQQLVAYYSKHADGLCHRLTN
VCPT
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1f1w Structural basis for specificity switching of the Src SH2 domain.
Resolution2.1 Å
Binding residue
(original residue number in PDB)
R155 R175 S177 E178 H201 Y202 K203 I214
Binding residue
(residue number reindexed from 1)
R12 R32 S34 E35 H58 Y59 K60 I71
Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
External links
PDB RCSB:1f1w, PDBe:1f1w, PDBj:1f1w
PDBsum1f1w
PubMed10911998
UniProtP00523|SRC_CHICK Proto-oncogene tyrosine-protein kinase Src (Gene Name=SRC)

[Back to BioLiP]