Structure of PDB 1f0v Chain A Binding Site BS01

Receptor Information
>1f0v Chain A (length=124) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHES
LADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTT
QANKHIIVACEGNPYVPVHFDASV
Ligand information
Receptor-Ligand Complex Structure
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PDB1f0v A domain-swapped RNase A dimer with implications for amyloid formation
Resolution1.7 Å
Binding residue
(original residue number in PDB)		H12 N44 T45 R85 E86
Binding residue
(residue number reindexed from 1)		H12 N44 T45 R85 E86
Enzymatic activity
Catalytic site (original residue number in PDB) H12 K41 H119 F120 D121
Catalytic site (residue number reindexed from 1) H12 K41 H119 F120 D121
Enzyme Commision number 4.6.1.18: pancreatic ribonuclease.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004519 endonuclease activity
GO:0004522 ribonuclease A activity
GO:0004540 RNA nuclease activity
GO:0005515 protein binding
GO:0016829 lyase activity
Biological Process
GO:0050830 defense response to Gram-positive bacterium
Cellular Component
GO:0005576 extracellular region

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Cellular Component
External links
PDB RCSB:1f0v, PDBe:1f0v, PDBj:1f0v
PDBsum1f0v
PubMed11224563
UniProtP61823|RNAS1_BOVIN Ribonuclease pancreatic (Gene Name=RNASE1)

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