Structure of PDB 1eyf Chain A Binding Site BS01

Receptor Information
>1eyf Chain A (length=92) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKKATCLTDDQRWQSVLARDPNADGEFVFAVRTTGIFCRPSCRARHALRE
NVSFYANASEALAAGFRPCKRCQPDKANPRQHRLDKITHACR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1eyf Chain A Residue 93 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1eyf Structural basis for the functional switch of the E. coli Ada protein
ResolutionN/A
Binding residue
(original residue number in PDB)		C38 C42 C69 C72
Binding residue
(residue number reindexed from 1)		C38 C42 C69 C72
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) C38 C42 C69 C72
Catalytic site (residue number reindexed from 1) C38 C42 C69 C72
Enzyme Commision number 2.1.1.63: methylated-DNA--[protein]-cysteine S-methyltransferase.
2.1.1.n11: methylphosphotriester-DNA--[protein]-cysteine S-methyltransferase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0008168 methyltransferase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006281 DNA repair
GO:0006355 regulation of DNA-templated transcription

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1eyf, PDBe:1eyf, PDBj:1eyf
PDBsum1eyf
PubMed11284682
UniProtP06134|ADA_ECOLI Bifunctional transcriptional activator/DNA repair enzyme Ada (Gene Name=ada)

[Back to BioLiP]