Structure of PDB 1el1 Chain A Binding Site BS01

Receptor Information
>1el1 Chain A (length=130) Species: 9615 (Canis lupus familiaris) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SKIFSKCELARKLKSMGMDGFHGYSLANWVCMAEYESNFNTQAFNGRNSN
GSSDYGIFQLNSKWWCKSNSHSSANACNIMCSKFLDDNIDDDIACAKRVV
KDPNGMSAWVAWVKHCKGKDLSKYLASCNL
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1el1 Chain A Residue 130 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1el1 Expression of a Synthetic Gene Encoding Canine Milk Lysozyme in Escherichia Coli and Characterization of The Expressed Protein
Resolution1.9 Å
Binding residue
(original residue number in PDB)		K82 D85 N87 D90 D91
Binding residue
(residue number reindexed from 1)		K83 D86 N88 D91 D92
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) E35 N47 N49 S51 D53 N60
Catalytic site (residue number reindexed from 1) E36 N48 N50 S52 D54 N61
Enzyme Commision number 3.2.1.17: lysozyme.
Gene Ontology
Molecular Function
GO:0003796 lysozyme activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0046872 metal ion binding
Biological Process
GO:0031640 killing of cells of another organism
GO:0042742 defense response to bacterium

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Molecular Function
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Biological Process
External links
PDB RCSB:1el1, PDBe:1el1, PDBj:1el1
PDBsum1el1
PubMed
UniProtP81708|LYSC1_CANLF Lysozyme C, milk isozyme

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