Structure of PDB 1ee4 Chain A Binding Site BS01
Receptor Information
>1ee4 Chain A (length=423) Species:
4932
(Saccharomyces cerevisiae) [
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QELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLV
EFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGS
VEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTAT
WTLSNLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSD
GPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQV
VINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIP
PLVKLLEVAEDKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDL
LEIADNRIIEVTLDALENILKMGEADKEARGLNINENADFIEKAGGMEKI
FNCQQNENDKIYEKAYKIIETYF
Ligand information
>1ee4 Chain C (length=9) Species:
9606
(Homo sapiens) [
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PAAKRVKLD
Receptor-Ligand Complex Structure
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PDB
1ee4
Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin alpha.
Resolution
2.1 Å
Binding residue
(original residue number in PDB)
S116 E118 W153 N157 A159 S160 G161 Q192 W195 N199 D203 W237 N241 R244 D276 W279
Binding residue
(residue number reindexed from 1)
S30 E32 W67 N71 A73 S74 G75 Q106 W109 N113 D117 W151 N155 R158 D190 W193
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:1ee4
,
PDBe:1ee4
,
PDBj:1ee4
PDBsum
1ee4
PubMed
10745017
UniProt
Q02821
|IMA1_YEAST Importin subunit alpha (Gene Name=SRP1)
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