Structure of PDB 1ee4 Chain A Binding Site BS01

Receptor Information
>1ee4 Chain A (length=423) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLV
EFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGS
VEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTAT
WTLSNLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSD
GPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQV
VINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIP
PLVKLLEVAEDKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDL
LEIADNRIIEVTLDALENILKMGEADKEARGLNINENADFIEKAGGMEKI
FNCQQNENDKIYEKAYKIIETYF
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1ee4 Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin alpha.
Resolution2.1 Å
Binding residue
(original residue number in PDB)
S116 E118 W153 N157 A159 S160 G161 Q192 W195 N199 D203 W237 N241 R244 D276 W279
Binding residue
(residue number reindexed from 1)
S30 E32 W67 N71 A73 S74 G75 Q106 W109 N113 D117 W151 N155 R158 D190 W193
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:1ee4, PDBe:1ee4, PDBj:1ee4
PDBsum1ee4
PubMed10745017
UniProtQ02821|IMA1_YEAST Importin subunit alpha (Gene Name=SRP1)

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