Structure of PDB 1eba Chain A Binding Site BS01

Receptor Information
>1eba Chain A (length=212) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KFESKAALLAARGPEELLCFTERLEDLVCFWEEAASAGVGPGNYSFSYQL
EDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPLELRVTAASGAPRY
HRVIHINEVVLLDAPVGLVARLADESGHVVLRWLPPPETPMTSHIRYEVD
VSAGGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAW
SEPVSLLTPSDL
Ligand information
Receptor-Ligand Complex Structure
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PDB1eba An antagonist peptide-EPO receptor complex suggests that receptor dimerization is not sufficient for activation.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		L33 S92 P149 M150 T151 S152 F205
Binding residue
(residue number reindexed from 1)		L24 S83 P140 M141 T142 S143 F193
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004896 cytokine receptor activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:1eba, PDBe:1eba, PDBj:1eba
PDBsum1eba
PubMed9808045
UniProtP19235|EPOR_HUMAN Erythropoietin receptor (Gene Name=EPOR)

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