Structure of PDB 1eb6 Chain A Binding Site BS01

Receptor Information
>1eb6 Chain A (length=177) Species: 5062 (Aspergillus oryzae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TEVTDCKGDAESSLTTALSNAAKLANQAAEAAESGDESKFEEYFKTTDQQ
TRTTVAERLRAVAKEAGSTSGGSTTYHCNDPYGYCEPNVLAYTLPSKNEI
ANCDIYYSELPPLAQKCHAQDQATTTLHEFTHAPGVYQPGTEDLGYGYDA
ATQLSAQDALNNADSYALYANAIELKC
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1eb6 Chain A Residue 178 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1eb6 A Quick Solution: Ab Initio Structure Determination of a 19 kDa Metalloproteinase Using Acorn
Resolution1.0 Å
Binding residue
(original residue number in PDB)		H128 H132 D143
Binding residue
(residue number reindexed from 1)		H128 H132 D143
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) Y106 H128 E129 H132 D143
Catalytic site (residue number reindexed from 1) Y106 H128 E129 H132 D143
Enzyme Commision number 3.4.24.39: deuterolysin.
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0008237 metallopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1eb6, PDBe:1eb6, PDBj:1eb6
PDBsum1eb6
PubMed11679721
UniProtP46076|NPII_ASPOR Neutral protease 2 (Gene Name=AO090010000493)

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