Structure of PDB 1e4u Chain A Binding Site BS01

Receptor Information
>1e4u Chain A (length=78) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSRSPDAKEDPVECPLCMEPLEIDDINFFPCTCGYQICRFCWHRIRTDEN
GLCPACRKPYPEDPAVYKPLSQEELQRI
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1e4u Chain A Residue 79 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1e4u The Structure of the C4C4 Ring Finger of Human not4 Reveals Features Distinct from Those of C3Hc4 Ring Fingers
ResolutionN/A
Binding residue
(original residue number in PDB)
C14 C17 C38 C41
Binding residue
(residue number reindexed from 1)
C14 C17 C38 C41
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Gene Ontology
Molecular Function
GO:0004842 ubiquitin-protein transferase activity
Cellular Component
GO:0030014 CCR4-NOT complex

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Molecular Function

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Cellular Component
External links
PDB RCSB:1e4u, PDBe:1e4u, PDBj:1e4u
PDBsum1e4u
PubMed11087754
UniProtO95628|CNOT4_HUMAN CCR4-NOT transcription complex subunit 4 (Gene Name=CNOT4)

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