Structure of PDB 1e3b Chain A Binding Site BS01

Receptor Information
>1e3b Chain A (length=172) Species: 6239 (Caenorhabditis elegans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSRSKVFFDITIGGKASGRIVMELYDDVVPKTAGNFRALCTGENGIGKSG
KPLHFKGSKFHRIIPNFMIQGGDFTRGNGTGGESIYGEKFPDENFKEKHT
GPGVLSMANAGPNTNGSQFFLCTVKTEWLDGKHVVFGRVVEGLDVVKAVE
SNGSQSGKPVKDCMIADCGQLK
Ligand information
Ligand ID3EP
InChIInChI=1S/C6H15P/c1-4-7(5-2)6-3/h4-6H2,1-3H3
InChIKeyRXJKFRMDXUJTEX-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341
OpenEye OEToolkits 1.5.0		CCP(CC)CC
ACDLabs 10.04P(CC)(CC)CC
FormulaC6 H15 P
NameTRIETHYLPHOSPHANE
ChEMBL
DrugBank
ZINCZINC000001846538
PDB chain1e3b Chain A Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1e3b First Crystal Structure of a Medicinally Relevant Gold Protein Complex:Unexpected Binding of [Au(Pet (3))](+) to Histidine
Resolution1.85 Å
Binding residue
(original residue number in PDB)		W128 K132
Binding residue
(residue number reindexed from 1)		W128 K132
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) R62 F67 Q70 N109 F120 L129 H133
Catalytic site (residue number reindexed from 1) R62 F67 Q70 N109 F120 L129 H133
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
Gene Ontology
Molecular Function
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
GO:0005515 protein binding
GO:0016018 cyclosporin A binding
Biological Process
GO:0000413 protein peptidyl-prolyl isomerization
GO:0006457 protein folding
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1e3b, PDBe:1e3b, PDBj:1e3b
PDBsum1e3b
PubMed11028014
UniProtP52011|CYP3_CAEEL Peptidyl-prolyl cis-trans isomerase 3 (Gene Name=cyn-3)

[Back to BioLiP]