Structure of PDB 1e28 Chain A Binding Site BS01

Receptor Information
>1e28 Chain A (length=276) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRTEPRPP
WIEQEGPEYWDRNTQIFKTNTQTYRENLRIALRYYNQSEAGSHTWQTMYG
CDVGPDGRLLRGHNQYAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
REAEQLRAYLEGLCVEWLRRHLENGKETLQRADPPKTHVTHHPVSDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
>1e28 Chain C (length=8) Species: 11676 (Human immunodeficiency virus 1) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
TAFTIPSI
Receptor-Ligand Complex Structure
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PDB1e28 Nonstandard peptide binding revealed by crystal structures of HLA-B*5101 complexed with HIV immunodominant epitopes.
Resolution3.0 Å
Binding residue
(original residue number in PDB)
Y7 R62 N63 I66 N70 N77 I80 W95 Y99 Y116 T143 W147 E152 L156 Y159 L163
Binding residue
(residue number reindexed from 1)
Y7 R62 N63 I66 N70 N77 I80 W95 Y99 Y116 T143 W147 E152 L156 Y159 L163
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:1e28, PDBe:1e28, PDBj:1e28
PDBsum1e28
PubMed10975842
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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