Structure of PDB 1dzm Chain A Binding Site BS01

Receptor Information
>1dzm Chain A (length=149) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PFELSGKWITSYIGSSDLEKIGENAPFQVFMRSIEFDDKESKVYLNFFSK
ENGICEEFSLIGTKQEGNTYDVNYAGNNKFVVSYASETALIISNINVDEE
GDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIPEENIVNIIERDDCPA
Ligand information
Ligand IDBZM
InChIInChI=1S/C14H12O2/c15-14(13-9-5-2-6-10-13)16-11-12-7-3-1-4-8-12/h1-10H,11H2
InChIKeySESFRYSPDFLNCH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0c1ccc(cc1)COC(=O)c2ccccc2
ACDLabs 10.04
CACTVS 3.341		O=C(OCc1ccccc1)c2ccccc2
FormulaC14 H12 O2
NameBENZOIC ACID PHENYLMETHYLESTER
ChEMBLCHEMBL1239
DrugBankDB00676
ZINCZINC000000001021
PDB chain1dzm Chain A Residue 600 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1dzm Complexes of Porcine Odorant Binding Protein with Odorant Molecules Belonging to Different Chemical Classes
Resolution1.93 Å
Binding residue
(original residue number in PDB)		M39 V80 N102 M114 T115 G116
Binding residue
(residue number reindexed from 1)		M31 V72 N94 M106 T107 G108
Annotation score1
Binding affinityMOAD: ic50=3.9uM
PDBbind-CN: -logKd/Ki=5.41,IC50=3.9uM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005549 odorant binding
GO:0036094 small molecule binding
Biological Process
GO:0007608 sensory perception of smell
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1dzm, PDBe:1dzm, PDBj:1dzm
PDBsum1dzm
PubMed10864504
UniProtP81245|OBP_PIG Odorant-binding protein

[Back to BioLiP]