Structure of PDB 1dzk Chain A Binding Site BS01

Receptor Information
>1dzk Chain A (length=148) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FELSGKWITSYIGSSDLEKIGENAPFQVFMRSIEFDDKESKVYLNFFSKE
NGICEEFSLIGTKQEGNTYDVNYAGNNKFVVSYASETALIISNINVDEEG
DKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIPEENIVNIIERDDCPA
Ligand information
Ligand IDPRZ
InChIInChI=1S/C9H14N2O/c1-7(2)6-8-9(12-3)11-5-4-10-8/h4-5,7H,6H2,1-3H3
InChIKeyUXFSPRAGHGMRSQ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04O(c1nccnc1CC(C)C)C
OpenEye OEToolkits 1.5.0CC(C)Cc1c(nccn1)OC
CACTVS 3.341COc1nccnc1CC(C)C
FormulaC9 H14 N2 O
Name2-ISOBUTYL-3-METHOXYPYRAZINE
ChEMBLCHEMBL97355
DrugBankDB04512
ZINCZINC000000156517
PDB chain1dzk Chain A Residue 700 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1dzk Complexes of Porcine Odorant Binding Protein with Odorant Molecules Belonging to Different Chemical Classes
Resolution1.48 Å
Binding residue
(original residue number in PDB)		F35 M39 M114
Binding residue
(residue number reindexed from 1)		F26 M30 M105
Annotation score1
Binding affinityMOAD: Kd=0.8uM
PDBbind-CN: -logKd/Ki=6.10,Kd=0.8uM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005549 odorant binding
GO:0036094 small molecule binding
Biological Process
GO:0007608 sensory perception of smell
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1dzk, PDBe:1dzk, PDBj:1dzk
PDBsum1dzk
PubMed10864504
UniProtP81245|OBP_PIG Odorant-binding protein

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