Structure of PDB 1dzj Chain A Binding Site BS01

Receptor Information
>1dzj Chain A (length=148) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FELSGKWITSYIGSSDLEKIGENAPFQVFMRSIEFDDKESKVYLNFFSKE
NGICEEFSLIGTKQEGNTYDVNYAGNNKFVVSYASETALIISNINVDEEG
DKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIPEENIVNIIERDDCPA
Ligand information
Ligand IDSES
InChIInChI=1S/C10H18N2Se/c1-3-5-7-8-9(6-4-2)13-10(11)12-8/h3-7H2,1-2H3,(H2,11,12)
InChIKeyDOUUMUUUWUAPPC-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04n1c(c([se]c1N)CCC)CCCC
CACTVS 3.341CCCCc1nc(N)[se]c1CCC
OpenEye OEToolkits 1.5.0CCCCc1c([se]c(n1)N)CCC
FormulaC10 H18 N2 Se
Name4-butyl-5-propyl-1,3-selenazol-2-amine
ChEMBLCHEMBL1235902
DrugBankDB01740
ZINC
PDB chain1dzj Chain A Residue 700 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1dzj Complexes of Porcine Odorant Binding Protein with Odorant Molecules Belonging to Different Chemical Classes
Resolution2.0 Å
Binding residue
(original residue number in PDB)		L53 Y82 F88 I100
Binding residue
(residue number reindexed from 1)		L44 Y73 F79 I91
Annotation score1
Binding affinityMOAD: ic50=1.3uM
PDBbind-CN: -logKd/Ki=5.89,IC50=1.3uM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005549 odorant binding
GO:0036094 small molecule binding
Biological Process
GO:0007608 sensory perception of smell
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1dzj, PDBe:1dzj, PDBj:1dzj
PDBsum1dzj
PubMed10864504
UniProtP81245|OBP_PIG Odorant-binding protein

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