Structure of PDB 1dxm Chain A Binding Site BS01

Receptor Information

>1dxm Chain A (length=131) Species: 3888 (Pisum sativum)

SNVLDGLKYAPSHEWVKHEGSVATIGITDHAQDHLGEVVFVELPEPGVSV
TKGKGFGAVESVKATSDVNSPISGEVIEVNTGLTGKPGLINSSPYEDGWM
IKIKPTSPDELESLLGAKEYTKFCEEEDAAH

Ligand information

• Ligand ID: RED
• InChI: InChI=1S/C8H16O2S2/c9-8(10)4-2-1-3-7(12)5-6-11/h7,11-12H,1-6H2,(H,9,10)/t7-/m1/s1
• InChIKey: IZFHEQBZOYJLPK-SSDOTTSWSA-N
• SMILES:
  OpenEye OEToolkits 1.5.0: C(CCC(=O)O)CC(CCS)S
  OpenEye OEToolkits 1.5.0: C(CCC(=O)O)C[C@H](CCS)S
  ACDLabs 10.04: O=C(O)CCCCC(S)CCS
  CACTVS 3.341: OC(=O)CCCC[C@@H](S)CCS
  CACTVS 3.341: OC(=O)CCCC[CH](S)CCS
• Formula: C8 H16 O2 S2
• Name: DIHYDROLIPOIC ACID
• ChEMBL: CHEMBL1235647
• DrugBank: DB03760
• ZINC: ZINC000003869601
• PDB chain: 1dxm Chain A Residue 163

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1dxm Interaction between the Lipoamide-Containing H-Protein and the Lipoamide Dehydrogenase (L-Protein) of the Glycine Decarboxylase Multienzyme System. 2. Crystal Structure of H- and L-Proteins
• Resolution: 2.6 Å
• Binding residue (original residue number in PDB): H34 L35 K63 E127
• Binding residue (residue number reindexed from 1): H34 L35 K63 E127
• Annotation score: 4

Gene Ontology

Biological Process

• GO:0019464 glycine decarboxylation via glycine cleavage system

Cellular Component

• GO:0005960 glycine cleavage complex

External links

• PDB: RCSB:1dxm, PDBe:1dxm, PDBj:1dxm
• PDBsum: 1dxm
• PubMed: 10806386
• UniProt: P16048|GCSH_PEA Glycine cleavage system H protein, mitochondrial (Gene Name=GDCSH)