Structure of PDB 1dsz Chain A Binding Site BS01

Receptor Information
>1dsz Chain A (length=75) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVT
RNRCQYCRLQKCFEVGMSKESVRND
Ligand information
Receptor-Ligand Complex Structure
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PDB1dsz Structure of the RXR-RAR DNA-binding complex on the retinoic acid response element DR1.
Resolution1.7 Å
Binding residue
(original residue number in PDB)
Y1145 H1146 Y1147 K1156 V1205 R1206
Binding residue
(residue number reindexed from 1)
Y12 H13 Y14 K23 V72 R73
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:1dsz, PDBe:1dsz, PDBj:1dsz
PDBsum1dsz
PubMed10698945
UniProtP10276|RARA_HUMAN Retinoic acid receptor alpha (Gene Name=RARA)

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