Structure of PDB 1dhy Chain A Binding Site BS01

Receptor Information
>1dhy Chain A (length=278) Species: 306 (Pseudomonas sp.) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SIERLGYLGFAVKDVPAWDHFLTKSVGLMAAGSAGDAALYRADQRAWRIA
VQPGELDDLAYAGLEVDDAAALERMADKLRQAGVAFTRGDEALMQQRKVM
GLLCLQDPFGLPLEIYYGPAEIFHEPFLPSAPVSGFVTGDQGIGHFVRCV
PDTAKAMAFYTEVLGFVLSDIIDIVPAHFLHCNGRHHTIALAAFPIPKRI
HHFMLQANTIDDVGYAFDRLDAAGRITSLLGRHTNDQTLSFYADTPSPMI
EVEFGWGPRTVWTVARHSRTAMWGHKSV
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain1dhy Chain A Residue 293 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1dhy Three-dimensional structures of free form and two substrate complexes of an extradiol ring-cleavage type dioxygenase, the BphC enzyme from Pseudomonas sp. strain KKS102.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		H145 H209 E260
Binding residue
(residue number reindexed from 1)		H145 H202 E253
Annotation score1
Enzymatic activity
Enzyme Commision number 1.13.11.39: biphenyl-2,3-diol 1,2-dioxygenase.
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0005506 iron ion binding
GO:0008198 ferrous iron binding
GO:0018583 biphenyl-2,3-diol 1,2-dioxygenase activity
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity
Biological Process
GO:0009056 catabolic process
GO:0042178 xenobiotic catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1dhy, PDBe:1dhy, PDBj:1dhy
PDBsum1dhy
PubMed8636975
UniProtP17297|BPHC_PSES1 Biphenyl-2,3-diol 1,2-dioxygenase (Gene Name=bphC)

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