Structure of PDB 1dct Chain A Binding Site BS01

Receptor Information
>1dct Chain A (length=324) Species: 725 (Haemophilus influenzae biotype aegyptius) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNLISLFSGAGGLDLGFQKAGFRIICANEYDKSIWKTYESNHSAKLIKGD
ISKISSDEFPKCDGIIGGPPCQSWSEGGSLRGIDDPRGKLFYEYIRILKQ
KKPIFFLAENVKGMMAQRHNKAVQEFIQEFDNAGYDVHIILLNANDYGVA
QDRKRVFYIGFRKELNINYLPPIPHLIKPTFKDVIWDLKDNPIPALDKNK
TNGNKCIYPNHEYFIGSYSTIFMSRNRVRQWNEPAFTVQASGRQCQLHPQ
APVMLKVSKNLNKFVEGKEHLYRRLTVRECARVQGFPDDFIFHYESLNDG
YKMIGNAVPVNLAYEIAKTIKSAL
Ligand information
Receptor-Ligand Complex Structure
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PDB1dct The crystal structure of HaeIII methyltransferase convalently complexed to DNA: an extrahelical cytosine and rearranged base pairing.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		G68 P70 C71 S75 E76 G77 G78 S79 R81 R87 E109 V111 R155 R225 R227 R229 F236 T237 Q239 Q244 N306
Binding residue
(residue number reindexed from 1)		G68 P70 C71 S75 E76 G77 G78 S79 R81 R87 E109 V111 R155 R225 R227 R229 F236 T237 Q239 Q244 N306
Enzymatic activity
Enzyme Commision number 2.1.1.37: DNA (cytosine-5-)-methyltransferase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003886 DNA (cytosine-5-)-methyltransferase activity
GO:0005524 ATP binding
GO:0008168 methyltransferase activity
Biological Process
GO:0009307 DNA restriction-modification system
GO:0032259 methylation

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Molecular Function
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Biological Process
External links
PDB RCSB:1dct, PDBe:1dct, PDBj:1dct
PDBsum1dct
PubMed7606780
UniProtP20589|MTH3_HAEAE Type II methyltransferase M.HaeIII (Gene Name=haeIIIM)

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