Structure of PDB 1d5z Chain A Binding Site BS01

Receptor Information
>1d5z Chain A (length=178) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFA
SFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREP
NVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLP
FLPSTEDVYDCRVEHWGLDEPLLKHWEF
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1d5z Peptide and peptide mimetic inhibitors of antigen presentation by HLA-DR class II MHC molecules. Design, structure-activity relationships, and X-ray crystal structures.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		Q9 E11 I31 W43 S53 F54 N62 V65 D66 N69
Binding residue
(residue number reindexed from 1)		Q7 E9 I29 W41 S51 F52 N60 V63 D64 N67
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:1d5z, PDBe:1d5z, PDBj:1d5z
PDBsum1d5z
PubMed10841792
UniProtP01903|DRA_HUMAN HLA class II histocompatibility antigen, DR alpha chain (Gene Name=HLA-DRA)

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