Structure of PDB 1d4t Chain A Binding Site BS01

Receptor Information
>1d4t Chain A (length=104) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGY
IYTYRVSQTETGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQY
PVEK
Ligand information
Receptor-Ligand Complex Structure
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PDB1d4t Crystal structures of the XLP protein SAP reveal a class of SH2 domains with extended, phosphotyrosine-independent sequence recognition.
Resolution1.1 Å
Binding residue
(original residue number in PDB)		R13 E17 Y50 I51 Y52 T53 Y54 R55 E67 T68 A69 V72 R75 D91 G93
Binding residue
(residue number reindexed from 1)		R13 E17 Y50 I51 Y52 T53 Y54 R55 E67 T68 A69 V72 R75 D91 G93
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006968 cellular defense response
GO:0007267 cell-cell signaling
Cellular Component
GO:0005737 cytoplasm

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Biological Process
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Cellular Component
External links
PDB RCSB:1d4t, PDBe:1d4t, PDBj:1d4t
PDBsum1d4t
PubMed10549287
UniProtO60880|SH21A_HUMAN SH2 domain-containing protein 1A (Gene Name=SH2D1A)

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