Structure of PDB 1cyx Chain A Binding Site BS01

Receptor Information
>1cyx Chain A (length=158) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KPITIEVVSMDWKWFFIYPEQGIATVNEIAFPANTPVYFKVTSNSVMHSF
FIPRLGSQIYAMAGMQTRLHLIANEPGTYDGICAEICGPGHSGMKFKAIA
TPDRAAFDQWVAKAKQSPNTMSDMAAFEKLAAPSEYNQVEYFSNVKPDLF
ADVINKFM
Ligand information
Ligand IDCUA
InChIInChI=1S/2Cu
InChIKeyALKZAGKDWUSJED-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Cu][Cu]
FormulaCu2
NameDINUCLEAR COPPER ION
ChEMBL
DrugBank
ZINC
PDB chain1cyx Chain A Residue 316 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1cyx Crystal structure of the membrane-exposed domain from a respiratory quinol oxidase complex with an engineered dinuclear copper center.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		H172 C207 E209 C211 H215
Binding residue
(residue number reindexed from 1)		H48 C83 E85 C87 H91
Annotation score1
Enzymatic activity
Enzyme Commision number 1.10.3.-
Gene Ontology
Molecular Function
GO:0004129 cytochrome-c oxidase activity
GO:0005507 copper ion binding
GO:0009486 cytochrome bo3 ubiquinol oxidase activity
Biological Process
GO:0022900 electron transport chain
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1cyx, PDBe:1cyx, PDBj:1cyx
PDBsum1cyx
PubMed8618822
UniProtP0ABJ1|CYOA_ECOLI Cytochrome bo(3) ubiquinol oxidase subunit 2 (Gene Name=cyoA)

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