Structure of PDB 1csz Chain A Binding Site BS01
Receptor Information
>1csz Chain A (length=112) Species:
9606
(Homo sapiens) [
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GSRRASVGSHEKMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNNGSY
ALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQLVEHYSYKADGLLR
VLTVPCQKIGTQ
Ligand information
>1csz Chain B (length=5) Species:
9606
(Homo sapiens) [
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TYETL
Receptor-Ligand Complex Structure
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PDB
1csz
Solution structure of the C-terminal SH2 domain of the human tyrosine kinase Syk complexed with a phosphotyrosine pentapeptide.
Resolution
N/A
Binding residue
(original residue number in PDB)
R22 A51 L61 H62 Y63 R64 I75 E77 G78 Y91 G97 L98
Binding residue
(residue number reindexed from 1)
R22 A51 L61 H62 Y63 R64 I75 E77 G78 Y91 G97 L98
Enzymatic activity
Enzyme Commision number
2.7.10.2
: non-specific protein-tyrosine kinase.
External links
PDB
RCSB:1csz
,
PDBe:1csz
,
PDBj:1csz
PDBsum
1csz
PubMed
8590001
UniProt
P43405
|KSYK_HUMAN Tyrosine-protein kinase SYK (Gene Name=SYK)
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