Structure of PDB 1cp6 Chain A Binding Site BS01

Receptor Information

>1cp6 Chain A (length=291) Species: 671 (Vibrio proteolyticus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MPPITQQATVTAWLPQVDASQITGTISSLESFTNRFYTTTSGAQASDWIA
SEWQALSASLPNASVKQVSHSGYNQKSVVMTITGSEAPDEWIVIGGHLDS
TIGSHTNEQSVAPGADDDASGIAAVTEVIRVLSENNFQPKRSIAFMAYAA
EEVGLRGSQDLANQYKSEGKNVVSALQLDMTNYKGSAQDVVFITDYTDSN
FTQYLTQLMDEYLPSLTYGFDTCGYACSDHASWHNAGYPAAMPFESKFND
YNPRIHTTQDTLANSDPTGSHAKKFTQLGLAYAIEMGSATG

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

1cp6 Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	1cp6 1-Butaneboronic acid binding to Aeromonas proteolytica aminopeptidase: a case of arrested development.
Resolution	1.9 Å
Binding residue (original residue number in PDB)	D117 E152 H256
Binding residue (residue number reindexed from 1)	D117 E152 H256
Annotation score	4

Enzymatic activity

Catalytic site (original residue number in PDB)	H97 D117 E151 E152 D179 H256
Catalytic site (residue number reindexed from 1)	H97 D117 E151 E152 D179 H256
Enzyme Commision number	3.4.11.10: bacterial leucyl aminopeptidase.

Gene Ontology

	Molecular Function
GO:0008235	metalloexopeptidase activity

	Biological Process
GO:0006508	proteolysis

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Molecular Function

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Biological Process

External links

PDB	RCSB:1cp6, PDBe:1cp6, PDBj:1cp6
PDBsum	1cp6
PubMed	10413478
UniProt	Q01693\|AMPX_VIBPR Bacterial leucyl aminopeptidase

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