Structure of PDB 1cjx Chain A Binding Site BS01
Receptor Information
>1cjx Chain A (length=352) Species:
294
(Pseudomonas fluorescens) [
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YENPMGLMGFEFIEFASPTPGTLEPIFEIMGFTKVATHRSKNVHLYRQGE
INLILNNEPNSIASYFAAEHGPSVCGMAFRVKDSQKAYNRALELGAQPIH
IDTGPMELNLPAIKGIGGAPLYLIDRFGEGSSIYDIDFVYLEGVERNPVG
AGLKVIDHLTHNVYRGRMVYWANFYEKLFNFREARYFDIKGEYTGLTSKA
MSAPDGMIRIPLNEESSKGAGQIEEFLMQFNGEGIQHVAFLTDDLVKTWD
ALKKIGMRFMTAPPDTYYEMLEGRLPDHGEPVDQLQARGILLDGSSVEGD
KRLLLQIFSETLMGPVFFEFIQRKGDDGFGEGNFKALFESIERDQVRRGV
LA
Ligand information
Ligand ID
FE2
InChI
InChI=1S/Fe/q+2
InChIKey
CWYNVVGOOAEACU-UHFFFAOYSA-N
SMILES
Software
SMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Fe+2]
CACTVS 3.341
[Fe++]
Formula
Fe
Name
FE (II) ION
ChEMBL
DrugBank
DB14510
ZINC
PDB chain
1cjx Chain A Residue 629 [
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Receptor-Ligand Complex Structure
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PDB
1cjx
Crystal structure of Pseudomonas fluorescens 4-hydroxyphenylpyruvate dioxygenase: an enzyme involved in the tyrosine degradation pathway.
Resolution
2.4 Å
Binding residue
(original residue number in PDB)
H161 H240 E322
Binding residue
(residue number reindexed from 1)
H158 H237 E319
Annotation score
1
Enzymatic activity
Enzyme Commision number
1.13.11.27
: 4-hydroxyphenylpyruvate dioxygenase.
Gene Ontology
Molecular Function
GO:0003868
4-hydroxyphenylpyruvate dioxygenase activity
GO:0016701
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
GO:0046872
metal ion binding
GO:0051213
dioxygenase activity
Biological Process
GO:0006559
L-phenylalanine catabolic process
GO:0006572
tyrosine catabolic process
GO:0009072
aromatic amino acid metabolic process
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Molecular Function
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Biological Process
External links
PDB
RCSB:1cjx
,
PDBe:1cjx
,
PDBj:1cjx
PDBsum
1cjx
PubMed
10467142
UniProt
P80064
|HPPD_PSEUJ 4-hydroxyphenylpyruvate dioxygenase (Gene Name=hpd)
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