Structure of PDB 1c07 Chain A Binding Site BS01

Receptor Information
>1c07 Chain A (length=95) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TWVVSPAEKAKYDEIFLKTDKDMDGFVSGLEVREIFLKTGLPSTLLAHIW
SLCDTKDCGKLSKDQFALAFHLISQKLIKGIDPPHVLTPEMIPPS
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1c07 Chain A Residue 110 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1c07 Solution structure of Eps15's third EH domain reveals coincident Phe-Trp and Asn-Pro-Phe binding sites.
ResolutionN/A
Binding residue
(original residue number in PDB)		D28 D30 D32 F34 V35 E39
Binding residue
(residue number reindexed from 1)		D20 D22 D24 F26 V27 E31
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:1c07, PDBe:1c07, PDBj:1c07
PDBsum1c07
PubMed10757979
UniProtP42566|EPS15_HUMAN Epidermal growth factor receptor substrate 15 (Gene Name=EPS15)

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