Structure of PDB 1bw8 Chain A Binding Site BS01

Receptor Information
>1bw8 Chain A (length=256) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSG
MPECKFGMNDKIKQSIAIDDCTFHQCVRLSERSISFIPPDGEFELMRYRT
TKDIILPFRVIPLVREVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPTPLN
TSGVQVICMKGKAKYKASENAIVWKIKRMAGMKESQISAEIELLPTNDKK
KWARPPISMNFEVPFAPSGLKVRYLKVFEPKLNYSDHDVIKWVRYIGRSG
IYETRC
Ligand information
Receptor-Ligand Complex Structure
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PDB1bw8 A structural explanation for the recognition of tyrosine-based endocytotic signals.
Resolution2.65 Å
Binding residue
(original residue number in PDB)		F174 D176 K203 L404 K420 W421 V422 R423
Binding residue
(residue number reindexed from 1)		F16 D18 K45 L225 K241 W242 V243 R244
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0030131 clathrin adaptor complex

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Biological Process
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Cellular Component
External links
PDB RCSB:1bw8, PDBe:1bw8, PDBj:1bw8
PDBsum1bw8
PubMed9812899
UniProtP84092|AP2M1_RAT AP-2 complex subunit mu (Gene Name=Ap2m1)

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