Structure of PDB 1bt4 Chain A Binding Site BS01

Receptor Information
>1bt4 Chain A (length=361) Species: 1397 (Niallia circulans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SERAYNFNAGPAALPLEVLERAQAEFVDYQHTGMSIMEMSHRGAVYEAVH
NEAQARLLALLGNPTGYKVLFIQGGASTQFAMIPMNFLKEGQTANYVMTG
SWASKALKEAKLIGDTHVAASSEASNYMTLPKLQEIQLQDNAAYLHLTSN
ETIEGAQFKAFPDTGSVPLIGDMSSDILSRPFDLNQFGLVYAGAQKNLGP
SGVTVVIVREDLVAESPKHLPTMLRYDTYVKNNSLYNTPPSFGIYMVNEV
LKWIEERGGLEGVQQANRKKASLIYDAIDQSGGFYRGCVDVDSRSDMNIT
FRLASEELEKEFVKASEQEGFVGLKGHRSVGGLRASIYNAVPYESCEALV
QFMEHFKRSRG
Ligand information
Ligand IDPLP
InChIInChI=1S/C8H10NO6P/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14/h2-3,11H,4H2,1H3,(H2,12,13,14)
InChIKeyNGVDGCNFYWLIFO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341Cc1ncc(CO[P](O)(O)=O)c(C=O)c1O
OpenEye OEToolkits 1.5.0Cc1c(c(c(cn1)COP(=O)(O)O)C=O)O
ACDLabs 10.04O=P(O)(O)OCc1cnc(c(O)c1C=O)C
FormulaC8 H10 N O6 P
NamePYRIDOXAL-5'-PHOSPHATE;
VITAMIN B6 Phosphate
ChEMBLCHEMBL82202
DrugBankDB00114
ZINCZINC000001532514
PDB chain1bt4 Chain A Residue 363 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1bt4 Phosphoserine Aminotransferase from Bacillus Circulans Subsp. Alkalophilus: Purification, Gene Cloning and Sequencing
Resolution2.3 Å
Binding residue
(original residue number in PDB)		A77 S78 W103 D173 S175 Q196 K197
Binding residue
(residue number reindexed from 1)		A76 S77 W102 D172 S174 Q195 K196
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) W103 D173 K197
Catalytic site (residue number reindexed from 1) W102 D172 K196
Enzyme Commision number 2.6.1.52: phosphoserine transaminase.
Gene Ontology
Molecular Function
GO:0004648 O-phospho-L-serine:2-oxoglutarate aminotransferase activity
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0006563 L-serine metabolic process
GO:0006564 L-serine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1bt4, PDBe:1bt4, PDBj:1bt4
PDBsum1bt4
PubMed
UniProtQ59196|SERC_NIACI Phosphoserine aminotransferase (Gene Name=serC)

[Back to BioLiP]