Structure of PDB 1bmo Chain A Binding Site BS01

Receptor Information
>1bmo Chain A (length=233) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PCQNHHCKHGKVCELDENNTPMCVCQDPTSCPAPIGEFEKVCSNDNKTFD
SSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIPPCLDSELTEFPLRMRDW
LKNVLVTLYERDEDNNLLTEKQKLRVKKIHENEKRLEAGDHPVELLARDF
EKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFF
ETCDLDNDKYIALDEWAGCFGIKQKDIDKDLVI
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1bmo Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1bmo Crystal structure of a pair of follistatin-like and EF-hand calcium-binding domains in BM-40.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		D222 P225 D227 Y229 E234
Binding residue
(residue number reindexed from 1)		D169 P172 D174 Y176 E181
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Cellular Component
GO:0005615 extracellular space

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Molecular Function
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Cellular Component
External links
PDB RCSB:1bmo, PDBe:1bmo, PDBj:1bmo
PDBsum1bmo
PubMed9233787
UniProtP09486|SPRC_HUMAN SPARC (Gene Name=SPARC)

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